Name two common adverse effects of NSAIDs that Unit Clerks should document.

• A. Gastrointestinal upset and kidney function impact
• B. Hypertension and edema
• C. Dizziness and hair loss
• D. Visual changes and tinnitus

Answer: (A)

NSAIDs commonly irritate the gastrointestinal tract and can impair kidney function, so documentation should focus on these two areas. Prostaglandin inhibition diminishes the protective lining of the stomach, leading to GI upset, dyspepsia, nausea, abdominal pain, ulcers, or even bleeding. It also reduces renal perfusion and can cause decreased urine output or rising creatinine/BUN, especially in older adults, those who are dehydrated, or patients taking other kidney-affecting drugs. While other effects like edema or dizziness can occur in some cases, the most frequent and clinically important adverse effects to record for NSAIDs are gastrointestinal irritation and changes in kidney function. If the patient has symptoms suggesting GI bleeding or signs of kidney dysfunction, these should be documented and reported promptly.